Dr Eddy Littler United Kingdom

Domainex is a drug discovery company with a reputation for speed and innovation built on an exceptional track record of drug candidate delivery. It has a world class discovery team with an unrivalled track record and three client drug candidates already in clinic.

Domainex reduces industry average drug discovery timelines by as much as 30% through the application of novel proprietary technologies and a highly focussed and integrated approach to medicinal chemistry and computational chemistry. These technologies and Domainex’s approach also enable it to successfully tackle a greater range of drug target classes, such as kinases, proteases, ion channels, proteins involved in epigenetics and protein-protein interactions.

 Domainex has applied its unique technologies and focussed discovery approach to enable it to develop its own pipeline of oncology drugs, including inhibitors of the kinases IKKε/TBK1 for both oncology and inflammation and a number of epigenetics related lysine methyltransferases, including G9a

Company type
Domainex
Chief Executive Officer 

Rob Marchmont United Kingdom

Sphere Fluidics Limited is an innovative Life Sciences company which delivers miniaturised products, systems and collaboration services in field of single cell analysis.

Sphere’s core technology is in the field of high throughput Picodroplet generation and analysis and has significant patent portfolio that protects its core expertise. It enables ultra-high throughput analysis of single cells and generation of their genetic, transcriptomic and proteomic profiles in miniaturised (pl to nl) volumes.  

Uniquely, as well as allowing single cell studies, the systems enable the study of different, large biomolecules that interact with or are secreted by those single cells. The latter application is very powerful as many human biotherapeutics, industrial enzymes (isolated mainly from micro-organisms) and around 15% of the Human Proteome are secreted, so cannot readily be analysed using conventional technology

Sphere Fluidics' technology enables diverse applications such as study of the mechanism of cancer cell resistance to chemotherapy, generation of new enzymes and identification of novel microbial strains.

Sphere Fluidics has established multiple commercial partnerships, received Venture Capital investment and with its founders the Company have received almost £10 million in science and business funding to date.

Company type
Sphere Fluidics Ltd
Commercial Director 

Dr Joanne McCudden United Kingdom

Domainex is a drug discovery company with a reputation for speed and innovation built on an exceptional track record of drug candidate delivery. It has a world class discovery team with an unrivalled track record and three client drug candidates already in clinic.

Domainex reduces industry average drug discovery timelines by as much as 30% through the application of novel proprietary technologies and a highly focussed and integrated approach to medicinal chemistry and computational chemistry. These technologies and Domainex’s approach also enable it to successfully tackle a greater range of drug target classes, such as kinases, proteases, ion channels, proteins involved in epigenetics and protein-protein interactions.

 Domainex has applied its unique technologies and focussed discovery approach to enable it to develop its own pipeline of oncology drugs, including inhibitors of the kinases IKKε/TBK1 for both oncology and inflammation and a number of epigenetics related lysine methyltransferases, including G9a

Company type
Domainex
Head of Business Development 

Ms Helen McKeever United Kingdom

Almac provides a comprehensive range of integrated services from research through to commercialisation.  Almac is a financially stable, privately owned organisation with over 3,300 employees located within the US and UK. Over 95% of work is repeat business, testament itself to the quality, innovation, efficiency and the high level of customer satisfaction provided.   

Services Offered
Almac’s integrated solutions extend from research to commercialisation and include:

Biomarker Discovery & Development:
·         Companion Diagnostic Development
·         Genomic Services
·         Bioinformatics Consultancy
·         Proprietary Discovery Arrays 

API Services & Chemical Development:
·         API Development & Manufacture
·         Peptide & Protein Technology
·         Accelerated First in Man Solution
·         Solid State Services
·         Isotope Chemistry
·         Biocatalysis
     
Pharmaceutical Development: 
·         Preformulation & Early Stage Development
·         Scale Up and Late Stage Development
·         Clinical Trial Manufacture
·         Contained Development & Manufacture

Analytical Services:
·         Physical & Chemical Characterisation
·         Method Development & Validation
·         API & Drug Product Testing
·         Stability Testing

Clinical Trial Supply:
·         Comparator Blinding
·         Packaging & Labelling
·         QP Release
·         Global Distribution & Supply Chain Management

Clinical Technologies:
·         IVR / Web
·         ePRO
·         Statistical Services

Commercial Services
·         Manufacturing & Packaging
·         Product Launch & Distribution

Come and see us at booth #64

Company type
Almac Group
Programme Manager 

Dr Dave Mead United Kingdom

Novozymes Biopharma develops and manufactures sustainable, safe, biological based ingredients and technologies to provide pharmaceutical and medical device manufacturers the knowledge-based solutions needed to address the challenges in developing innovative, safer, and more consistent final products. The company's large-scale manufacturing facilities worldwide are run to cGMP Q7 quality standards to ensure that customers receive the highest level of product quality and consistency, as well as the security of long-term supply. Novozymes’ customer-integrated approach combines the company’s scientific know-how and the specific needs of customers to deliver improved products and performance. By combining Novozymes’ unique knowledge around our biological solutions such as recombinant albuminhalf-life extension and hyaluronic acid with the specific application knowledge of our customers, we work with companies to deliver improved performance and safety for next generation of medical device and pharmaceutical products.
Novozymes Biopharma UK
LinkedIn logo Business Development Director 

Mr Peter Nolan United Kingdom

Oxford BioMedica (LSE:OXB) is a leading gene therapy and immunotherapy company with a platform of exclusive and pioneering technologies to design, develop and manufacture unique gene-based medicines. The Company’s technology platforms include a highly efficient LentiVector® gene delivery system; a single administration to provide long-lasting therapy with specific advantages for targeting CNS and ocular diseases, and a unique tumour antigen (5T4) which is an ideal target for anti-cancer therapy.

The Company’s pipeline addresses diseases for which there is currently no treatment or that are inadequately treated today, including ocular diseases, neurodegenerative disorders and cancer, and its product candidates have the potential to transform treatment landscapes.  Oxford BioMedica’s capabilities cover the entire product lifecycle, from research to development to GMP manufacturing, with collaborative partners such as Sanofi, Pfizer, Novartis and some of the most prestigious clinical centres worldwide.  The Company recently secured significant funding via UK Government competitive awards such as the TSB regenerative medicine/cell therapy grant and AMSCI to build a centre of excellence for specialist manufacture of gene-based therapies.

Through in-house development programmes and industry collaborations, Oxford BioMedica’s goal is to improve the lives of patients with debilitating and life-threatening diseases.  Further information is available at www.oxfordbiomedica.co.uk and www.oxbsolutions.co.uk.

Oxford BioMedica plc
SVP - Commercial Development 

Mr Vashu Pamnani United Kingdom

Cambridge Bioscience is a well established, leading European distributor of life science products bringing new and exciting technologies to researchers. Working with over forty specialist suppliers around the world, we offer an innovative, extensive and diverse range of over 450,000 products, services and instruments supporting research in the areas of drug discovery, regenerative medicine, cell culture and much more.

The products and services Cambridge Bioscience offers includes:
·         Ion Channel, GPCR & Kinase Profiling Services
·         Primary screening  & Secondary Drug Profiling Services
·         Cardiac Safety Assessment
·         Ion Channel & GPCR Cell Lines
·         Human Tissues, TMAs & Biofluids
·         Primary Cells & Cell Culture Technologies

To find out more, please meet us at the event or contact us using the details below
Cambridge Bioscience
Munro House
Trafalgar Way
Bar Hill
Cambridge 
United Kingdom
CB23 8SQ

Tel: +44 (0)1223 316 855
Fax: +44 (0)1954 781 323
Email: support@bioscience.co.uk
Website: www.bioscience.co.uk

Company type
Cambridge Bioscience
LinkedIn logo Business Manager 

Mr Christopher Parsons United Kingdom

UKTI London's private sector International Trade Advisers support London based companies to develop their business internationally. This is achieved via provision of advice, training and delivery of UKTI services.

Supported by the Mayor's Export Program UKTI London is bringing a trade mission to  Bio-Europe. Kit Malthouse the Deputy Mayor of London for Business and Enterprise will be meeting the mission delegates at a networking breakfast on Tuesday Nov 5th.

UK Trade & Investment - London Region
International Trade Adviser 

Dr Keith Powell United Kingdom

Canbex is dedicated to improving the quality of life for people with multiple sclerosis (MS) and potentially other disorders, through better treatment for spasticity. 

 

Spasticity is the sudden and uncontrollable movement of limbs and torso, and is among the most painful, damaging and debilitating symptoms of MS.  Current drug treatments for spasticity are effective but are plagued by sedative and other side effects that sharply limit their usefulness.

 

Canbex closed a $3.2m financing round led by Merck Serono Ventures in April 2013, and its lead anti-spasticity compound, VSN16R, is set to enter Phase I safety testing.  In studies to date, VSN16R shows substantially improved tolerability compared to other compounds, and is as effective against spasticity as any other agent known.

 

Supported by its leading London-based scientific and clinical team, Canbex believes that VSN16R has the potential to meet an important medical need, and to address a highly attractive commercial opportunity. 

 

To find out more, please meet us at the event or contact us using the details below

 

Canbex Therapeutics Ltd

London BioScience Innovation Centre

2 Royal College Street

London

NW1 0NH

Tel: +44 (0)207 554 5872

Email: enquiries@canbex.co.uk

Website:
www.canbex.co.uk
Canbex Therapeutics Ltd
Chairman 

Dr Miroslav Ravic United Kingdom

MGB Biopharma is a private company based in Glasgow, Scotland and is backed by a syndicate of Scotland’s leading angel investor groups together with Scottish Enterprise.

Antimicrobial drug resistance is recognised as a global public health concern with an urgent need for new antibacterial drug classes that are more effective than existing treatments. MGB is developing the first truly novel class of anti-infectives in over a decade that has the potential to treat infections of a number of the most important susceptible and resistant pathogens. Our lead compound has shown strong bactericidal activity with quick onset of action against many strains of Gram-positive bacteria. It has completed pre-clinical development and progress into our phase 1 clinical study for the treatment of Clostridium difficile have been endorsed by the MHRA. Optimisation of a new formulation for intravenous administration and treatment of systemic Gram-positive infection is ongoing.

MGB has acquired exclusive rights to the proprietary minor groove binder platform, developed at the University of Strathclyde, Glasgow. This platform provides an opportunity to develop additional compounds with the potential to treat Gram-negative, viral, fungal and parasitic infections.

MGB continues to work closely with Strathclyde University to develop the pipeline and is currently seeking partners to help maximise the value-creating opportunities from its broad platform.

Company type
MGB Biopharma