Novozymes Biopharma UK
Oxford BioMedica plc
Oxford BioMedica (LSE:OXB) is a leading gene therapy and immunotherapy company with a platform of exclusive and pioneering technologies to design, develop and manufacture unique gene-based medicines. The Company’s technology platforms include a highly efficient LentiVector® gene delivery system; a single administration to provide long-lasting therapy with specific advantages for targeting CNS and ocular diseases, and a unique tumour antigen (5T4) which is an ideal target for anti-cancer therapy.
The Company’s pipeline addresses diseases for which there is currently no treatment or that are inadequately treated today, including ocular diseases, neurodegenerative disorders and cancer, and its product candidates have the potential to transform treatment landscapes. Oxford BioMedica’s capabilities cover the entire product lifecycle, from research to development to GMP manufacturing, with collaborative partners such as Sanofi, Pfizer, Novartis and some of the most prestigious clinical centres worldwide. The Company recently secured significant funding via UK Government competitive awards such as the TSB regenerative medicine/cell therapy grant and AMSCI to build a centre of excellence for specialist manufacture of gene-based therapies.
Through in-house development programmes and industry collaborations, Oxford BioMedica’s goal is to improve the lives of patients with debilitating and life-threatening diseases. Further information is available at www.oxfordbiomedica.co.uk and www.oxbsolutions.co.uk.
Dr Alex LewisDirector of Corporate Activities & Strategy
Mr Peter NolanSVP - Commercial Development
A leader in ion exchange and resin technology—and one of the world’s largest
developers and manufacturers of high-quality APIs, blood purification polymers, enzyme carriers, chromatographic resins and ion exchange products—Purolite is introducing the new product line based on agarose in our cGMP, FDA regulated facility.
With three strategically located production plants, five global R&D centers—including a research center of excellence in the UK—and a sales force made up of industry experts, Purolite is your solutions company for quality products, stability of manufacturing and knowledgeable service.
Developed and manufactured by Purolite, innovative agarose-based biochromatography resins will expand the LifeTech family of products to cover SEC, HIC, IEX and affinity bio-purification media for the fast-growing biosimilars market.
LifeTech bio-based resins will support customer needs—from drug development with pre-packed columns, to bulk media for industrial production of biosimilars.
Dr Alessandra BassoLifeTech Manager
QCTR is the ONLY CRO to focus exclusively on clinical trials in CNS.
With its subjective assessments and often subjective diagnosis, along with lack of biomarkers and high placebo response, CNS offers unique challenges.
QCTR have over 15 years of experience in CNS covering diseases as diverse as Alzheimer's, TBI, stroke and schizophrenia, and orphan diseases such as Huntington's and FTD.
With a worldwide network of experienced clinicans working in neurology and psychiatry, and experienced staff knowledgable in the therapeutic field, we can plan and execute cost effective clinical trials to meet your company's specific requirements.
Dr Audrey JamiesonBusiness Development Manager
Selcia Ltd is a leading provider of contract research services in drug discovery and 14C radiolabelling.
Selcia drug discovery provides integrated drug discovery services to support academics, institutions, biotech and pharma companies. Selcia assist in grant applications; execute the medicinal chemistry to deliver the best drug candidates, provide supporting project management and primary pharmacology, to ensure project success.
Selcia radiolabelling specialises in 14C GMP radiolabelling and produces 14C radiolabelled compounds for a global customer base encompassing both the life sciences and chemical industries. Applications of the radiolabelled products prepared by Selcia include: preclinical and clinical drug metabolism studies; mass balance, microdosing, research and regulatory studies; and environmental fate studies.
The purity and structure of our products are assured by our internal MHRA GLP accredited analytical department with 500MHz, 400MHz & 300MHz NMRs, mass spec and separation specialists. The group are experts in problem resolution to ensure projects meet agreed milestones.
Areas of Expertise:
- Medicinal chemistry: Small molecules, macrocycles, natural product chemistry
- Disease expertise: Anti-infectives, inflammation, CNS, pain, metabolic
- Target classes: GPCRs, ion channels, enzymes, isomerases
- 14C Custom Radiosynthesis
- GMP Radiolabelled API for Clinical Trials
- GLP/GMP Analytics – GLP NMR
- Metabolites and Impurities (Profiling and Synthesis), standards and stable labelled compounds
Mr Dave RobertsBD Director Radiochemistry
Sphere Fluidics Ltd
Sphere Fluidics Limited is an innovative Life Sciences company which delivers miniaturised products, systems and collaboration services in field of single cell analysis.
Sphere’s core technology is in the field of high throughput Picodroplet generation and analysis and has significant patent portfolio that protects its core expertise. It enables ultra-high throughput analysis of single cells and generation of their genetic, transcriptomic and proteomic profiles in miniaturised (pl to nl) volumes.
Uniquely, as well as allowing single cell studies, the systems enable the study of different, large biomolecules that interact with or are secreted by those single cells. The latter application is very powerful as many human biotherapeutics, industrial enzymes (isolated mainly from micro-organisms) and around 15% of the Human Proteome are secreted, so cannot readily be analysed using conventional technology
Sphere Fluidics' technology enables diverse applications such as study of the mechanism of cancer cell resistance to chemotherapy, generation of new enzymes and identification of novel microbial strains.
Sphere Fluidics has established multiple commercial partnerships, received Venture Capital investment and with its founders the Company have received almost £10 million in science and business funding to date.
Rob MarchmontCommercial Director
David HolmesPrincipal Engineer
Sygnature Discovery Limited
Sygnature Discovery, founded in 2004 in Nottingham, UK, is a leading provider of integrated drug discovery services to pharmaceutical companies, biotechs and academics located in Europe and the USA. Through its unique ‘federated’ CRO model, Sygnature undertakes complete drug discovery programmes and hit finding, hit-to-lead and lead optimisation projects for its clients. The company employs 75 laboratory-based, industry-experienced PhD medicinal chemists, computational chemists and in vitro biologists.
Working within the highly-complex, competitive and fast-paced pharmaceutical and biotech sectors, Sygnature has developed a unique approach to offering a premium integrated drug discovery service – the delivery of in-depth, pharmaceutical industry-derived drug discovery expertise and flexible FTE-based resource housed in a ‘state-of-the-art’ R&D facility, but at a cost effective price. From the outset, Sygnature has operated a business whose primary focus has been value creation for its clients, through the application of drug discovery expertise, close working relationships and complete transparency.
To facilitate the delivery of top quality drug discovery services to its clients, Sygnature has strategic alliances with Cyprotex Discovery (ADME/toxicology), Saretius (pre-clinical pain/CNS and metabolic disease models), Pneumolabs (pre-clinical respiratory models), Horizon Discovery (X-ManTM isogenic cell lines), ChanTest (ion channel experts) and Proteros (X-ray protein structure analysis).
For more information, visit: www.sygnaturediscovery.com and www.integrateddrugdiscovery.com.
Synpromics is a life science company focused on synthetic biology. Our core proprietary technology enables the design of optimized Synthetic Promoters to more effectively and efficiently regulate gene expression throughout biotechnology applications. Via product-development and distribution partnerships, Synpromics will commercially apply our novel promoters to enhance and expedite life science R&D, improve biology-based production processes, advance agricultural biotech and progress personalized medicine.
Dr Michael RobertsChief Executive Officer
UK Trade & Investment - London Region
UKTI London's private sector International Trade Advisers support London based companies to develop their business internationally. This is achieved via provision of advice, training and delivery of UKTI services.
Supported by the Mayor's Export Program UKTI London is bringing a trade mission to Bio-Europe. Kit Malthouse the Deputy Mayor of London for Business and Enterprise will be meeting the mission delegates at a networking breakfast on Tuesday Nov 5th.